MBD 3 | Methyl-CpG-binding Domain 3

Methyl-CpG-binding domain protein 3 also known as MBD3 is a nuclear protein belonging to the NURD complex family with a MBD (methyl-CpG-binding) domain. This DNA associated, transcription factor is involved in chromatin remodeling and methylates DNA. MBD3 acts as a transcriptional repressor and plays a role in gene silencing.